Job Description
Position Description
We are seeking an exceptional and highly motivated informatician to join the Cheminformatics group within Modeling and Informatics (M&I) at our company. This role requires strong interpersonal and problem-solving skills and experience working in a cross-functional team environment. It involves both the development of innovative computational methods involving AI/ML and cheminformatics, as well as direct application of advanced computational approaches to the invention of novel medicines.
M&I is an inclusive team within our Research & Development Division Discovery Chemistry organization, comprising approximately 50 computational chemists, cheminformaticians, and data scientists. We leverage cutting-edge capabilities in structure-based modeling, predictive science, and AI/ML to drive drug design and development globally, with a proven track record of pipeline impact. The selected candidate will work closely with the M&I team, our world-class chemistry teams, as well as cross-functionally with experimental and computational colleagues in the early target discovery space on innovative science that has a wealth of opportunities to impact drug discovery and ultimately save and improve patient lives.
Key responsibilities will include:
- Implement and apply effective AI/ML and cheminformatics workflows to impact early target discovery space data analysis.
- Analyze, interpret, and summarize complex chemical biology data and utilize a variety of data visualization tools to communicate findings.
- Deliver optimized informatics algorithms and workflows to expedite drug discovery pipelines in the early target discovery space for small molecules, peptides, and targeted protein degraders.
- Leverage novel ML, statistics, and cheminformatics techniques to improve hit identification for different screening paradigms.
- Analyze and integrate internal and external knowledge to facilitate biological and chemical signature identification.
- Proactively engage with cross-functional teams of experimental and computational scientists and collaborate effectively to advance project and pipeline goals
- Continue research in areas of AI/ML and cheminformatics relevant to drug discovery, and evaluate new technology and software from commercial sources, open innovation, or external collaborations.
- Effectively communicate scientific results internally and externally through presentations and publications.
- Share AI/ML and/or data engineering knowledge to augment team skills and capabilities.
Position Qualifications:
Education Minimum Requirement:
Ph.D. in